The health care revolution is not just an opportunity but an urgent and essential need. Our existing health care models are not sustainable in the long run. The cost of health spending continues to rise with the rapid worldwide growth of costly chronic diseases. Meanwhile, the global health care workforce faces a predicted shortfall of 18 million health workers by 2030, a gap which will accelerate the necessary adoption of digital technologies. Yet while these trends are widely acknowledged, health care organizations and stakeholders need to recognize that we now also have the tools for transformation, which will not only drive efficacy of care and personalization, but also, and equally importantly, better access and efficiency.